Relevant Publications
Metabolic
Miricorilant, a selective GR modulator, induced a rapid and significant reduction in liver fat content in a randomized, placebo-controlled phase 2a study in patients with nonalcoholic steatohepatitis
- Kowdley et al
- 2021
The Liver Meeting 2021 (American Association for the Study of Liver Diseases)
Oncology
Relacorilant, A Selective Glucocorticoid Receptor Modulator, In Combination With Nab-Paclitaxel Improves Progression-Free Survival In Patients With Recurrent Platinum-Resistant Ovarian Cancer: A 3-Arm, Randomized, Open-Label, Phase 2 Study
- Lorusso et al.
- 2021
European Society for Medical Oncology (ESMO) Congress 2021
Oncology
Glucocorticoid receptor antagonism promotes apoptosis in solid tumor cells
- Greenstein et al.
- 2021
- 34194622
Oncotarget . 2021 Jun 22;12(13):1243-1255. doi: 10.18632/oncotarget.27989.
Oncology
Adrenal tumors provide insight into the role of cortisol in NK cell activity
- Greenstein et al.
- 2021
- 34086600
Endocr Relat Cancer . 2021 Jun 29;28(8):583-592. doi: 10.1530/ERC-21-0048.
Metabolic
Effect of Miricorilant, a Selective Glucocorticoid Receptor Modulator, on Olanzapine-Associated Weight Gain in Healthy Subjects: A Proof-of-Concept Study
- Hunt et al
- 2021
Journal of Clinical Psychopharmacology: August 6, 2021
Metabolic
Relacorilant, a Selective Glucocorticoid Receptor Modulator, Induces Clinical Improvements in Patients With Cushing Syndrome: Results From A Prospective, Open-Label Phase 2 Study
- Pivonello et al
- 2021
- 662865
Front. Endocrinol., 14 July 2021
Oncology
Suppression of Tumor Immune Activity in Adrenocortical Carcinoma with Excess Glucocorticoid
- Greenstein et al.
- 2020
AACR Annual Meeting 2020
Oncology
Impact of relacorilant, a selective glucocorticoid receptor antagonist, on the immunosuppressive effects of endogenous cortisol.
- Greenstein et al.
- 2020
Citation: J Clin Oncol 38: 2020 (suppl; abstract #: 3091)
Metabolic
Reversal of Antipsychotic-Induced Weight Gain in Rats with Miricorilant, a Selective Glucocorticoid Receptor (GR) Modulator
- Lee et al.
- 2020
2020 Annual Meeting - American Psychiatric Association (APA)
Metabolic
GRADIENT: A Phase 3, Double-Blind, Randomized, Placebo-Controlled Study to Assess the Efficacy and Safety of a Selective Glucocorticoid Receptor Modulator, Relacorilant, in Patients With Autonomous Cortisol Secretion Due to Cortisol-Secreting Adrenal Adenoma(s)/Hyperplasia
- Auchus et al.
- 2020
J Endocr Soc. Vol 4, Issue Suppl 1 April-May